This course presents the fundamental aspects of pathogenic microbiology including morphology, metabolism and replication of micro-organisms, the basic principles of the use of chemotherapeutic agents, microbial genetics, and medical microbial ecology. The major bacterial, viral, mycotic, and parasitic diseases of humans are covered in detail. The basic principles of immunology and infection in relation to clinical disease of the various body systems are discussed.

Bench research on the biology or the rickettsiales family of intracellular pathogens and on the pathogensis of the diseases caused by these organisms. Participation in ongoing research or inititation of new projects are possible.

Presents the fundamental aspects of microbiology including morphology, metabolism of micro-organisms, the basic principles of the use of antibiotics and chemotherapeutic agents, microbial genetics, virology, and medical microbial ecology. The principles of immunology and infection in relation to clinical disease are discussed with special emphasis on laboratory diagnosis.

Students and faculty participate in a supervised reading of the current literature and meet periodically to interact in a discussion of the selected article or topic. The goal of this course is to maintain the faculty's and students' level of information at a "state of the art" in both methods and theory in the discipline and to develop critical skills in reviewing the literature.

Students participate in research under the direction of a graduate faculty member. This course should be taken by students who have completed their lab rotations, but have not yet submitted a formal research proposal.

Each course provides in-depth tutorial exposure to specific areas in the discipline. Student and/or faculty presentations followed by group discussions, examine the subject matter in an area of current interest either to one student or a group of students. Credit and title are arranged with an individual faculty member.

This course discusses the fundamentals of this area with particular emphasis on Escherichia coli and Salmonella typhimurium as model systems. The development of problem solving skills will be stressed. Topics including aerobic vs. anaerobic metabolism, membrane physiology, biosynthesis of macromolecules and regulation of gene expression provide view of microbial cell.

Selected topics in immunology are considered using formal lectures followed by student presentations. Design and interpretation of immunological experiments are emphasized throughout the course.

This course reviews the reproductive cycles of important human viruses and subviral agents and the diseases they cause. The focus is on the molecular biology of animan viruses and their mechanisms of regulation, assembly, and pathogenesis. Human immunodeficiency virus will be considered in detail. The course is constructed as an interactive lecture series with student reports and literature surveys.

Students present a research topic for discussion before members of the department. Usually scheduled on a rotational basis. Student participation required after end of second year. Attendance required.

Independent research by the student under the sponsorship of the graduate faculty in individual departments in the Basic Medical Sciences. Students are required to submit a research project description form before enrolling in this course. Progress reports of the work accomplished are required every six months.